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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF5C
All Species:
5.76
Human Site:
S423
Identified Species:
9.05
UniProt:
O60282
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O60282
NP_004513.1
957
109495
S423
K
Y
D
E
E
I
S
S
L
Y
R
Q
L
D
D
Chimpanzee
Pan troglodytes
XP_525938
860
98662
E386
E
N
E
A
A
K
D
E
V
K
E
V
L
Q
A
Rhesus Macaque
Macaca mulatta
XP_001082054
860
98340
E386
E
N
E
A
A
K
D
E
V
K
E
V
L
Q
A
Dog
Lupus familis
XP_533351
955
109129
S422
K
Y
D
E
E
I
S
S
L
Y
R
Q
L
D
D
Cat
Felis silvestris
Mouse
Mus musculus
P28738
956
109222
L423
Y
D
E
E
I
T
S
L
Y
R
Q
L
D
D
K
Rat
Rattus norvegicus
Q6QLM7
1027
116897
R423
K
Y
E
E
E
I
R
R
L
Y
K
Q
L
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508129
965
109909
K427
K
C
E
E
E
I
A
K
L
Y
K
Q
L
D
D
Chicken
Gallus gallus
Q90640
1225
138905
N471
E
N
V
E
V
I
R
N
L
Q
Q
V
L
A
Q
Frog
Xenopus laevis
Q91784
1226
138905
N469
D
N
V
E
V
I
Q
N
L
Q
Q
V
I
V
Q
Zebra Danio
Brachydanio rerio
NP_001116747
985
113653
D419
Q
Y
E
E
L
I
N
D
L
Y
Q
Q
L
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17210
975
110381
R443
R
L
A
T
E
C
E
R
L
Y
Q
Q
L
D
D
Honey Bee
Apis mellifera
XP_395236
988
112484
R444
K
L
E
E
E
R
E
R
L
Y
Q
Q
L
D
D
Nematode Worm
Caenorhab. elegans
P34540
815
91875
A364
R
L
A
A
L
L
Q
A
A
A
L
E
L
S
R
Sea Urchin
Strong. purpuratus
P35978
1031
117504
K414
K
W
E
E
E
K
V
K
L
Y
E
Q
L
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48467
928
102392
S429
S
D
R
A
G
T
P
S
L
P
L
D
K
D
E
Conservation
Percent
Protein Identity:
100
89.8
85.5
98.3
N.A.
98
69.8
N.A.
75.2
26.3
24.8
76.8
N.A.
62
63.2
45.3
61.4
Protein Similarity:
100
89.8
86.4
98.9
N.A.
99.1
81.6
N.A.
86.4
45.3
45.5
86.9
N.A.
77.6
77.9
61.3
74.7
P-Site Identity:
100
6.6
6.6
100
N.A.
20
73.3
N.A.
66.6
26.6
20
60
N.A.
46.6
60
6.6
53.3
P-Site Similarity:
100
26.6
26.6
100
N.A.
33.3
86.6
N.A.
86.6
46.6
40
86.6
N.A.
60
73.3
33.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
31.7
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
52.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
14
27
14
0
7
7
7
7
0
0
0
7
14
% A
% Cys:
0
7
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
14
14
0
0
0
14
7
0
0
0
7
7
67
47
% D
% Glu:
20
0
54
67
47
0
14
14
0
0
20
7
0
0
14
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
7
47
0
0
0
0
0
0
7
0
0
% I
% Lys:
40
0
0
0
0
20
0
14
0
14
14
0
7
0
7
% K
% Leu:
0
20
0
0
14
7
0
7
74
0
14
7
80
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
27
0
0
0
0
7
14
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
14
0
0
14
40
54
0
14
14
% Q
% Arg:
14
0
7
0
0
7
14
20
0
7
14
0
0
0
7
% R
% Ser:
7
0
0
0
0
0
20
20
0
0
0
0
0
7
0
% S
% Thr:
0
0
0
7
0
14
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
14
0
14
0
7
0
14
0
0
27
0
7
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
27
0
0
0
0
0
0
7
54
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _